Sequence alignment scalable methods and accelerators

Design and development of new pairwise alignment algorithms and hardware accelerators that reduce the execution time and memory consumption

Institution:

Institution

Research Group:

High Performance Computing Applications for Science and Engineering (HPCA4SE)

Researcher/s:

Juan Carlos Moure, Santiago Marco, Antonio Espinosa

Description:

This project accelerates DNA sequence alignment by improving efficiency and reducing resource use. It uses optimized algorithms that lower memory needs and speed up processing, especially for large genomic datasets. It includes implementations for CPUs, GPUs, and FPGA accelerators, all using a common programming approach, enabling the same code to run across different systems. By moving only relevant data to accelerators and reducing data transfer, it improves performance and cuts energy use, supporting more efficient and scalable genomics workflows.

Value Proposition:

Accelerates long-read alignment with portable, energy-efficient FPGA/GPU kernels

Aplication areas:

Human & agricultural genomics, pathogen surveillance, precision-medicine pipelines, population-scale assembly projects, metagenomics

Target market:

Genome centres & biotech CROs handling >10 TB/day; Cloud providers offering GPU/FPGA genomics instances; Medical-devices firms integrating real-time pathogen ID; National sequencing initiatives building sovereign pipelines

Technology Readiness Level (1-9): N/A

Protection:

Pending

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